About Pneumonia

Key Facts

1

Pneumonia kills more children under the age of five than any other disease, claiming a young life every 20 seconds.

2

98% of all childhood deaths from pneumonia occur in developing nations.

3

Pneumonia is one of the most solvable problems in global health. We have the safe, effective and affordable tools necessary to help prevent children from contracting pneumonia and to treat those suffering with this illness.

4

The fight against pneumonia can be won. Estimates indicate that more than one million children’s lives can be saved annually with widespread use of vaccines and improved access to antibiotics.

5

Together we can ensure that pneumonia becomes a priority on the global health agenda, and that all parties work together to invest in its prevention. Join the Global Coalition against Child Pneumonia to take part in our global advocacy efforts.

Disease

What is pneumonia?

  • Pneumonia is an infection of the lungs, filling them with fluid.
  • It causes cough and fever and can make breathing difficult.
  • Severe pneumonia can be deadly.

Who is most at risk?

  • In developing countries, children under 5 years of age are at risk, especially in the poorest communities.[1]
  • Tobacco smoke and other indoor air pollution increase susceptibility to pneumonia.[2],[3]
  • Some children and adults are at greater risk because they have other illnesses, such as HIV/AIDS.[4], [5] People with HIV stand a much greater chance of dying from pneumonia than those who do not have HIV.[6]
  • Children who are poorly nourished can also have weakened immune systems, putting them at higher risk of contracting pneumonia.[7]

What causes pneumonia?

  • Globally, bacteria such as Hib and pneumococcus are estimated to cause more than 50% of pneumonia deaths in children under 5 years of age. [8]
  • Viruses and fungi can also cause pneumonia infections.[9]

How is pneumonia diagnosed?

  • In resource-poor settings, pneumonia can be diagnosed by the symptoms it causes, including cough, fever and difficulty or fast breathing.[10]
  • Chest X-rays and laboratory tests can also diagnose pneumonia, but these tools are often unavailable in developing countries, especially in remote rural communities, making it more difficult to diagnose and treat pneumonia.

How is pneumonia prevented and treated?

  • Some pneumonia can often be prevented with vaccines against Hib and pneumococcus.[11]
  • Measles and pertussis (whooping cough) infections can result in pneumonia complications, so vaccinating against these childhood diseases can prevent some pneumonia cases.[12]
  • Inexpensive antibiotics can effectively treat pneumonia at the community level.[13]

References

1 UNICEF/WHO. Pneumonia: the Forgotten Killer of Children. Geneva: 2006.
2 U.S. Department of Health and Human Services. The Health Consequences of Involuntary Exposure to Tobacco Smoke: A Report of the Surgeon General. Atlanta, Georgia: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, Coordinating Center for Health Promotion, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health; 2006.
3 Smith KR, Sarnet JM, Romieu I, Bruce N. Indoor air pollution in developing countries and acute lower respiratory infections in children. Thorax. 2000; 55:518-32.
4 SA Madhi, L Kuwanda, C Cutland and KP Klugman. The impact of a 9-valent pneumococcal conjugate vaccine on the public health burden of pneumonia in HIV-infected and –uninfected children. Clin Infect Dis. 2005; 40:1511-1518.
5 Feldman C. Pneumonia associated with HIV infection. Curr Opin Infect Dis. 2005; 18(2):165-70.
6 SA Madhi, K Petersen, A Madhi, A Wasas and KP Klugman. Impact of human immunodeficiency virus type I on the disease spectrum of Streptococcus pneumoniae in South African children. Pedatr Infect Dis J. 2000; 19:1131-1147.
7 Fishman SM, Caulfield LE, de Onix M, Blossner M, Hyder AA, Mullany L, et al,. Childhood and maternal underweight. In: Ezzati M, Lopez AD, Rodgers A, Murray CJL, eds. Comparative quantification of health risks: global and regional burden of disease attributable to selected major risk factors. Geneva: WHO; 2004.
8 In settings where these vaccines are not used. O’Brien K, Wolfoson L, Watt J, et al,. Burden of Disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates. Lancet. 2009; 374:893-902.
9 Mandell Lionel A, Wunderink Richard. Pneumonia. In: Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL, Jameson JL, Loscalzo J. Harrison’s Principles of Internal Medicine (17th ed.) New York: McGraw-Hill, 2008. http://www.accessmedicine.com. Accessed September 7, 2009.
10 World Health Organization and UNICEF. Integrated Managemenet of Childhood Illness Handbook. Geneva: World Health Organization, 2005.
11 Mahdi SA, Levine OS, Hajjeh R, Mansoor OD, Cherian T. Vaccines to prevent pneumonia and improve child survival. Bull World Health Organ. 2008; 86:365-72.
12 Mahdi SA, Levine OS, Hajjeh R, Mansoor OD, Cherian T. Vaccines to prevent pneumonia and improve child survival. Bull World Health Organ. 2008; 86:365-72.
13 Sazawal S, Black RE, Pneumonia Case Management Trials Group. Effect of pneumonia case management on mortality in neonates, infants, and pre-school children: a meta-analysis of community based trials. Lancet Infect Dis. 2003; 3:547-56.

Toll

  • More than one million children die from pneumonia each year. [1]
  • Pneumonia is the leading cause of death among children under 5 years of age worldwide.[2]
  • One child dies from pneumonia every 20 seconds.  That’s 4,300 young lives lost every day.[3]

Most children who die of pneumonia live in developing countries

  • 98% of children who die of pneumonia live in developing countries.[4], [5]

Pneumonia causes needless suffering and stress on families

  • Illness and hospitalization due to pneumonia are preventable sources of suffering and stress, as the disease is preventable with tools like Hib and pneumococcal vaccines, and the integrated collection of steps that can be taken to protect children.
  • Each year, there are more than 150 million episodes of pneumonia in young children in developing countries, and more than 11 million children need hospitalization for pneumonia.[6], [7]

Pneumonia contributes to the cycle of poverty

  • Pneumonia is an economic burden for families and communities.[8], [9]
  • The financial costs of pneumonia include hospital stays and medications, transportation to health centers, and the caretakers’ inability to work or take care of other family members while they are caring for a sick child.[10], [11]
  • Families often must take out large loans to pay for care of their seriously ill child, which may further drag them into deep poverty.
  • These costs further contribute to the cycle of poverty for many families.

References

1 Black R, Cousens S, Johnson H, et al. Global, regional, and national causes of child mortality in 2008: a systemic analysis. Lancet. 2010; 375:1969-87.
2 World Health Organization. World Health Statistics 2009. Geneva: World Health Organization; 2008. http://www.who.int/whosis/whostat/EN_WHS09_Full.pdf. Accessed September 6, 2009.
3 Black R, Cousens S, Johnson H, et al. Global, regional, and national causes of child mortality in 2008: a systemic analysis. Lancet. 2010; 375:1969-87.
4 World Health Organization. World health statistics 2006. Geneva: World Health Organization; 2006. http://www.who.int/whosis/whostat2006.pdf. Accessed September 6, 2009.
5 World Health Organization. World health statistics 2006. Geneva: World Health Organization; 2006. http://www.who.int/whosis/whostat2006.pdf. Accessed September 6, 2009.
6 Rudan I, Boschi-Pinto C, Biloglav Z, Mulholland K, Campbell H. Epidemiology and etiology of childhood pneumonia. Bull World Health Organ. 2008;86:408–16.
7 Rudan, I, Tomaskovic L, Boschi-Pinto C, Campbell H. Global estimate of the incidence of clinical pneumonia among children under five years of age. Bull World Health Organ. 2004;82:895–903.
8 Hussain H, Waters H, Khan AJ, Omer SB, Halsey NA. Economic analysis of childhood pneumonia in Northern Pakistan. Health Policy and Planning. 2008;23(6): 438-442.
9 Srivastava NM, Awasthi S, Agarwal GG. Care-seeking behavior and out-of-pocket expenditure for sick newborns among urban poor in Lucknow, northern India: a prospective follow-up study. BMC Health Services Research. 2009;9:61.
10 Avieko P, Akumu AO, Griffiths UK, English M. The economic burden of inpatient paediatric care in Kenya: household and provider costs for treatment of pneumonia, malaria and meningitis. Cost Effectiveness and Resource Allocation. 2009;7,3.
11 Madsen HO, Hanehøj M, Das AR, et al.. Costing of severe pneumonia in hospitalized infants and children aged 2–36 months, at a secondary and tertiary level hospital of a not-for-profit organization. Tropical Medical and International Health. 2009;14(10):1315-1322.

Pneumonia is a problem with solutions

More than ever before, we know how to protect children, to prevent them from becoming infected, and to treat infection. Every 20 seconds, pneumonia kills another child. That’s 4,300 child deaths every day, and a staggering 1+ million child deaths every year from a preventable, treatable disease.[1] Now is the time to put knowledge into action to deliver these solutions to all children around the world.

Get more details on strategies to fight pneumonia:

Protect | Prevent | Treat

 

 

We can protect from pneumonia

  • Exclusive breastfeeding during the first six months of life is an important and easy way to help protect children from pneumonia and many other diseases.[2]
  • Other strategies, like good nutrition for older children [3], hand-washing [4], and reducing indoor air pollution [5], [6] can also help protect children from pneumonia.

Preventing pneumonia before it occurs is key

  • Vaccines are a safe and effective tool for preventing pneumonia before it occurs.
  • Vaccines against two of the main causes of life-threatening pneumonia – pneumococcus (Streptococcus pneumoniae) and Hib (Haemophilus influenzae b) [7] – are used throughout the developed world.
  • However, millions of children in developing countries still lack access to these life-saving vaccines.
  • Measles and pertussis (ie. whooping cough) vaccines can prevent infections that can lead to pneumonia as a complication. [8]

Children should have access to effective and affordable treatment

  • Most serious cases of pneumonia can be treated using antibiotics, which typically cost less than one dollar per dose. [9]
  • Tragically, only an estimated 1 of every 5 children with pneumonia receives antibiotics. [10]
  • Effective “case management” strategies can help to ensure that children receive the right treatment for pneumonia quickly, even in the poorest communities. [11]

References

1 Black R, Cousens S, Johnson H, et al. Global, regional, and national causes of child mortality in 2008: a systematic analysis. Lancet. 2010; 375:1969-87.
2 Roth DE, Caulfield LE, Ezzati M, Black RE. Acute lower respiratory tract infections in childhood: opportunities for reducing the global burden through nutritional interventions. Bull World Health Organ 2008; 86:356-64.
3 Roth DE, Caulfield LE, Ezzati M, Black RE. Acute lower respiratory tract infections in childhood: opportunities for reducing the global burden through nutritional interventions. Bull World Health Organ 2008; 86:356-64.
4 Luby SP, Agboatwalla M, Freikin DR, Painter J, Billhimer W, Altaf A, Hockstra RM. Effect of handwashing on child health: a randomized controlled trial. Lancet. 2005; 366:225-233.
5 Smith KR, Sarnet JM, Romieu I, Bruce N. Indoor air pollution in developing countries and acute lower respiratory infections in children. Thorax. 2000; 55:518-32.
6 U.S. Department of Health and Human Services. The Health Consequences of Involuntary Exposure to Tobacco Smoke: A Report of the Surgeon General. Atlanta, Georgia: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, Coordinating Center for Health Promotion, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health; 2006. http://www.surgeongeneral.gov/library/secondhandsmoke/report/index.html. Accessed September 7, 2009.
7 O’Brien K, Wolfoson L, Watt J, et al,. Burden of Disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates. Lancet. 2009; 374:893-902.
8 Mahdi SA, Levine OS, Hajjeh R, Mansoor OD, Cherian T. Vaccines to prevent pneumonia and improve child survival. Bull World Health Organ. 2008; 86:365-72.
9 Sazawal S, Black RE, Pneumonia Case Management Trials Group. Effect of pneumonia case management on mortality in neonates, infants, and pre-school children: a meta-analysis of community based trials. Lancet Infect Dis. 2003; 3:547-56.
10 Figure based on multiple Demographic and Health Surveys (DHS), cited in Wardlaw T, Johansson EW, Hodge M. Pneumonia: the forgotten killer of children. New York: UNICEF, The World Bank; 2006.
11 Sazawal S, Black RE, Pneumonia Case Management Trials Group. Effect of pneumonia case management on mortality in neonates, infants, and pre-school children: a meta-analysis of community based trials. Lancet Infect Dis. 2003; 3:547-56.